Burt Gillett & Tom Palmer (1935)
Music by Winston Sharples
A girl is sewing in her playroom when a boy sneaks in and lets loose a horde of mice into her doll house. She discovers them and is fascinated by them, one in particular who can speak. They chat for a while, and the mouse tells them a story of a wizard friend who tried one day to make a potion that would render all things beautiful. He turns lizards into doves and a toad into a squirrel successfully, but when his back is turned another bottle accidentally opens up and spills into the beauty elixir. When he tries it on a batch of caged mice, they turn into little devils that chase him around his shop. They wreak havoc and eventually turn him into a giant rabbit, but he’s then saved by the doves, who mix a potion that reverts him to his human form and the devils back into mice.
That had to have been a first for the time. I tried to find out but couldn’t find a lot of info
That was quite an adventure. Neat how they started it out with live action.